Axonal Guidance and Synaptogenesis

Functional consequences of altered connectivity in schizophrenia; the early secretory pathway's role in neurodevelopment and synaptogenesis
Cellular and circuitry mechanisms underlying drug addiction and sleep regulation of reward.
Regulation of GABAergic inhibition in development and mental disorders
Motoneuron development and spinal cord patterning.
CNS stem cells.
Regulation and modulation of presynaptic ion channels and transmitter release in healthy and diseased synapses.
The goal of our research is to functionally dissect the neural circuits that underlie pain and itch.