George F. Wittenberg, MD, PhD

Visiting Professor, Neurology

Contact

3520 Fifth Ave, #201
412-648-4178
GEOWITT@pitt.edu
Website >

Focus

Restoration of voluntary movement after neurological injury.

Research Summary

Dr. Wittenberg’s overall goal is the restoration of voluntary movement after neurological injury and in neurological disorders. His ongoing research interests presently lie in using transcranial magnetic stimulation (TMS) and functional imaging to understand motor cortical reorganization following stroke and in designing and testing new methods for neurorehabilitation. He has been conducting clinical trials with robotic rehabilitation and continues to study the neural plasticity that underlies it. He is developing hybrid methods of combining TMS with robotic and virtual reality training, and multimodal physiological monitoring with feedback control of robotic assistance, to maximize the return of motor function after neurological injury by harnessing activity-dependent brain plasticity. Other interests in include bimanual rehabilitation and exploration of knowledge representation in the area of brain connectivity in order to understand and model human motor function. 

Publications

- Jones-Lush L, Judkins T, Wittenberg G. Arm movement maps evoked by cortical magnetic stimulation in a robotic environment. Neuroscience. 2010; 165(3):774-81.

- Krakauer JW, Carmichael ST, Corbett D, Wittenberg GF. Getting neurorehabilitation right: what can be learned from animal models? Neurorehabil Neural Repair. 2012 Oct; 26(8):923-31.

- Kantak S, Jones-Lush L, Narayanan P, Judkins T, Wittenberg G. Rapid plasticity of motor corticospinal system with robotic reach training. Neuroscience. 2013; 247:55-64.

- Massie CL, Kantak SS, Narayanan P, Wittenberg GF. Timing of motor cortical stimulation during planar robotic training differentially in older adults. Clin Neurophysiol. 2015; 126(5):1024-32.