Max Horowitz, PhD

Graduated

2012

Mentor

Dr. J. Timothy Greenamyre

Thesis

Current Affiliation

University of Pittsburgh School of Medicine

Current Position

Medical Student

Prior Degree

BS, University of California, Los Angeles (2003)

Publications

Horowitz, M.P., Montero, L.M., Cannon, J.R., Sew, T., Chu, C.T., Greenamyre, J.T. The alpha-synuclein regulatory transcription factor GATA2 is present in substantia nigra neurons and up-regulated in the rotenone rat. (In preparation).

Horowitz, M.P., Milanese, C., DiMaio, R., Hu, X., Montero, L.M., Sanders, L.H., Tapias, V., Burton, E.A., Greenamyre, J.T., Mastroberardino, P.G. Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative stress. (In revision).

Horowitz, M.P. and Greenamyre, J.T. Mitochondrial iron metabolism and its role in neurodegeneration. Journal of Alzheimer's Disease, 2010; 20 Suppl. 2: S551-68. [PMID: 20463401].

Horowitz, M.P. and Greenamyre, J.T. Gene-environment interactions in Parkinson's disease. Clinical Pharmacology and Therapeutics, 2010 Oct; 88(4): 467-74. [PMID: 20811350].

Marcu, J. P., Christian, R. T., Lau, D., Zielinski, A. J., Horowitz, M. P., Lee, J., Pakdel, A., Allison, J., Limbad, C., Moore, D. H., Yount, G. L., Desprez, P. Y., McAllister, S. D. Cannbidiol enhances the effects of ?9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival. Molecular Cancer Therapeutics, 2010 Jan 6 (Epub ahead of print).

Mastroberardino, P.G., Hoffman, E.K., Horowitz, M.P., Betarbet, R., Taylor, G., Cheng, D., Na, H.M., Gutekunst, C., Gearing, M., Trojanowski, J.Q, Anderson, M., Chu, C.T., Peng, J., Greenamyre, J.T. A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease. Neurobiology of Disease, 2009 Jun; 34(3):417-31. Epub 2009 Feb 26 [PMID: 19250966].

McAllister, S.D., Christian, R.T., Horowitz, M.P., Garcia, A. and Desprez, P.Y. Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. Molecular Cancer Therapeutics. 2007 Nov 6(11): 2921-7. [PMID: 18025276].