Neurobiology of Disease

Circuit dynamics underlying pathology and treatment of compulsive behaviors and anxiety disorders
Cellular and molecular mechanisms of neurodegeneration and neuroprotection.
Cognitive and Affective Neuroscience of Aging and Geriatric Brain Disorders
Mitochondria in neurodegeneration
Pathogenesis of Parkinson's diseases and progressive supranuclear palsy; development of novel neuroprotective strategies based on the underlying molecular pathophysiology.
Effects of everyday life stresses on behavior and health
Mechanisms of cell death and neuroprotection in cerebral ischemia and Parkinson's disease.
Cell signaling, dendritic morphogenesis and autophagy/mitophagy in neurodegenerative diseases
Glucocorticoid Regulation of Neurodevelopment.
Cellular and circuitry mechanisms underlying pathological neural plasticity
The molecular pathogenesis of Amyotrophic Lateral Sclerosis, Frontotemporal Dementia and similar age-dependent neurodegenerative diseases.
Neural circuits implicated in the development, pathophysiology, and treatment of schizophrenia and other major psychiatric disorders.
Functional consequences of altered connectivity in schizophrenia; the early secretory pathway's role in neurodevelopment and synaptogenesis
Developing a better understanding of the molecular mechanisms by which synaptic vesicles dynamically load, retain and release neurotransmitters such as dopamine and how these processes contribute to neuropsychiatric illnesses
Neural circuits in the basal ganglia involved in motor control and disease
Peripheral mechanisms of pain.
Neurophysiology of basal ganglia system related to psychiatric disorders.
Neuronal cell death in ischemia and trauma.
Mechanisms of neurodegeneration and neuroprotection in Parkinson's and Huntington's diseases.
Development, Disease and Regeneration of the Eye
Oxidative mechanisms associated with neurodegeneration.
Mechanism(s) of alcohol action.
The mechanism of neuroinflammation and immunotherapies for stroke
Cellular and circuit mechanisms underlying drug addiction and sleep-mediated regulation of reward.
Functional architecture of the prefrontal cortex and schizophrenia.
The molecular basis of psychiatric diseases.
Molecular mechanisms of neurodegenerative diseases.
Signal transduction pathways in glioma growth, molecular markers of glioma prognosis.
AMPA receptors in hearing and hearing loss. Ultrastructure and the chemical nature of the tripartite synapse
Fundamental and clinical research on cellular and molecular mechanisms of retinal degeneration and development of treatments for currently incurable blinding diseases
Functional neuroanatomy of cortical and brainstem monoamine systems.
Cell and molecular biology of dopamine transporter
CNS circuits of motor and cognitive functions; motor skill acquisition and retention; functional imaging.
Ion transporters in neurological diseases.
Mechanisms of psychosis in Alzheimer's disease and schizophrenia.
Neural mechanisms of auditory function and decision-making in the non-human primate
Cellular and molecular pathogenesis in Alzheimer's disease.
Determining developmental risk factors for addiction and novel treatments based on learning and memory systems.
Functions of the neural circuits that underpin motor performance and skill learning. Neural circuit dysfunction in Parkinson’s disease. Neuromodulation. Deep brain stimulation.
Molecular, cellular and system mechanisms underlying normal and pathological hearing
The impact of gender and changes in neurochemistry on rehabilitation and treatment outcomes after traumatic brain injury (TBI).
Examining mechanisms of neurodegeneration associated with Alzheimer's Disease, AIDS, West Nile Virus and influenza infection.
Neural Circuit Development and Dysfunction in Disease
Restoration of voluntary movement after neurological injury.
Gene and stem cell therapy in brain ischemia/membrane protein structure by NMR.
Mechanisms of neurovascular damage and repair in cerebral ischemia and traumatic brain injury