Silas Buck

E-mail

sib27@pitt.edu

Education & Training

B.S., Tulane University (2017)

Location

E1605 BSTWR

Mentor

Zachary Freyberg

Year

2018

Research Interest Summary

I am interested in using Drosophila to investigate dopamine neuron selective vulnerability in Parkinson’s disease

Buck, S. A., De Miranda, B. R., Logan, R. W., Fish, K. N., Greenamyre, J. T., Freyberg, Z (2021).
“VGLUT2 is a determinant of dopamine neuron resilience in a rotenone model of dopamine
neurodegeneration. ”Journal of Neuroscience, 41(22):4937-4947, PMID: 33893220.
https://doi.org/10.1523/JNEUROSCI.2770-20.2021


Buck, S. A., Steinkellner, T., Aslonoglou, D. Villeneuve, M., Bhatte, S. H., Childers, V., Rubin, S. A., De
Miranda, B. R., O’Leary, E. I., Neureiter, E. G., Fogle, K. J., Palladino, M. J., Logan, R. W., Glausier, J.
R., Fish, K. N., Lewis, D. A., Greenamyre, J. T., McCabe, B. D., Cheetham, C. E. J., Hnasko, T. S.,
Freyberg, Z (2021). “Vesicular glutamate transporter modulates sex differences in dopamine neuron
vulnerability to age-related neurodegeneration.”Aging Cell, 20:e13365, PMID: 3390313.
https://doi.org/10.1111/acel.13365


Buck, S. A., Torregrossa M. M., Logan, R. W., Freyberg, Z. (2020). “Roles of dopamine and glutamate
co-release in the nucleus accumbens in mediating the actions of drugs of abuse.” FEBS Journal. PMID:
32702182.