Representative Publications
Zhu X, Cabungcal JH, Cuenod M, Uliana DL, Do KQ, Grace AA. Thalamic reticular nucleus
impairments and abnormal prefrontal control of dopamine system in a developmental model of
schizophrenia: prevention by N-acetylcysteine. Mol Psychiatry. 2021 Jun 30. doi: 10.1038/s41380-021-
01198-8. Epub ahead of print. PMID: 34193975.
Zhu X, Grace AA. Prepubertal Environmental Enrichment Prevents Dopamine Dysregulation and
Hippocampal Hyperactivity in MAM Schizophrenia Model Rats. Biol Psychiatry. 2021 Feb 1;89(3):298-
307. doi: 10.1016/j.biopsych.2020.09.023. Epub 2020 Oct 5. PMID: 33357630; PMCID: PMC7927755.
Logan, R. W., A. R. Ozburn, R. N. Arey, K. D. Ketchesin, A. Winquist, A. Crain, B. T. D. Tobe, D.
Becker-Krail, M. B. Jarpe, X. Xue, W. Zong, Z. Huo, P. K. Parekh, X. Zhu, E. Fitzgerald, H. Zhang, J.
Oliver-Smith, L. M. DePoy, M. A. Hildebrand, E. Y. Snyder, G. C. Tseng and C. A. McClung (2020).
"Valproate reverses mania-like behaviors in mice via preferential targeting of HDAC2." Molecular
Psychiatry. https://doi.org/10.1038/s41380-020-00958-2
Gomes FV, Zhu X, Grace AA. The pathophysiological impact of stress on the dopamine system is
dependent on the state of the critical period of vulnerability. Mol Psychiatry. 2020 Dec;25(12):3278-3291.
doi: 10.1038/s41380-019-0514-1. Epub 2019 Sep 5. Erratum in: Mol Psychiatry. 2019 Sep 27;: PMID:
31488866; PMCID: PMC7056584
Gomes FV, Zhu X, Grace AA. Stress during critical periods of development and risk for schizophrenia.
Schizophr Res. 2019 Nov;213:107-113. doi: 10.1016/j.schres.2019.01.030. Epub 2019 Jan 30. PMID:
30711313; PMCID: PMC6667322.
Logan, R.W., Parekh, P.K., Williams, W.P.III, Kaplan, G.N., Becker-Krail, D., Yamaguchi S., Yoshino J., Shelton M., Zhu, X., Zhang, H, Waplinger, S., Fitzgerald, E., Oliver-Smith J., Sundaravelu P., Enwright J.III. McClung C.A. (2018), NAD+ cellular redox and SIRT1 regulate the diurnal rhythms of tyrosine hydroxylase and conditioned cocaine reward. Molecular Psychiatry.
Zhu, X., Gomes, F.V. and Grace, A.A. (2017). The methylazoxymethanol acetate rat model: molecular and epigenetic effect in the developing prefrontal cortex. J. Neurochem., 143: 264–267.
Logan, R.W., Edgar, N.M., Gillman, A.G., Hoffman, D., Zhu, X. and McClung, C.A., (2016). Chronic stress induces physiological and brain region specific molecular disruptions of circadian amplitude in mice. Biological Psychiatry.
